hh14000000 microlab star liquid handling system hamilton (Thermo Fisher)
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hh14000000 microlab star liquid handling system hamilton
Hh14000000 Microlab Star Liquid Handling System Hamilton, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hh14000000+microlab+star+liquid+handling+system+hamilton/HH14000000+Microlab+STAR+Liquid+Handling+System+Hamilton/pm34520744-472-104-142
Average 90 stars, based on 1 article reviews
Hh14000000 Microlab Star Liquid Handling System Hamilton, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hh14000000+microlab+star+liquid+handling+system+hamilton/HH14000000+Microlab+STAR+Liquid+Handling+System+Hamilton/pm34520744-472-104-142
Average 90 stars, based on 1 article reviews
hh14000000 microlab star liquid handling system hamilton - by Bioz Stars,
2026-09
90/100 stars
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Negative Control:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# Positive Control:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# Software:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# Drug discovery:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# High Content Screening:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# Real-time Polymerase Chain Reaction:Article Title: Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EndoFree Plasmid Maxi Kit Qiagen Cat# 12362 TaqMan Gene Expression Master Mix Applied Biosystems Cat# 10525395 Nano-Glo Live Cell Assay Solution Promega Cat# N2011 NIS TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs00166567_m1 PPIA TaqMan Gene Expression Assay ThermoFisher Scientific Cat# Hs04194521_s1 VCP TaqMan Gene Expression Assay ThermoFisher Scientific Cat# HS00997642_m1 Deposited data The Connectivity Map (CMAP) Subramanian et al., 2017 https://clue.io/touchstone Data source file This paper Mendeley Data: https://doi.org/10.17632/ vf3xnyxyp9.1 GSE27155 Giordano et al., 2005 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE27155 GSE76039 Landa et al., 2016 https://www.ncbi.nlm.nih.gov/geo/geo2r/? acc=GSE76039 TCGA GDAC Firehose standard data – Thyroid Carcinoma (THCA) Broad Institute of MIT and Harvard Firehose stddata__2016_01_28 run. https:// doi.org/10.7908/C11G0KM9 TCGA THCA Grossman et al., 2016 https://portal.gdc.cancer.gov/projects/ TCGA-THCA Thyroid carcinoma (TCGA, Firehose Legacy) Cerami et al., 2012; Gao et al., 2013 https://www.cbioportal.org/study/ summary?id=thca_tcga Experimental Models: Cell Lines TPC-1 Rebecca Schweppe’s lab N/A TPC-1-YFP This paper N/A TPC-1-NIS-YFP This paper N/A 8505C DSMZ Cat# ACC-219, RRID:CVCL_1054 8505C-YFP This paper N/A 8505C-NIS-YFP This paper N/A MDA-MB-231 ECACC Cat# 92020424, RRID:CVCL_0062 MCF7 ECACC Cat# 86012803, RRID:CVCL_0031 MDA-MB-231-NIS Fletcher et al., 2020 N/A HeLa ECACC Cat# 93021013, RRID:CVCL_0030 Oligonucleotides MISSION VCP siRNA Sigma-Aldrich Cat# NM_007126 LgBiT (Forward)5’-GCCAAGCTTAC CATGGTCTTCACACTCGAA-3’ Sigma-Aldrich Custom synthesis LgBiT (Reverse)5’-GGCGGTACCAC TGTTGATGGTTA CTCG-3’ Sigma-Aldrich Custom synthesis VCP (Forward)5’-GCGGTACCGCTT CTGGAGCCGATTCA-3’ Sigma-Aldrich Custom synthesis VCP (Reverse)5’-GCCGCCTCTAG ATTAGCCATACAGGTCATC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Forward)5’-GCCGGTACC ACCATGGAGGCCGTGGAGACC-3’ Sigma-Aldrich Custom synthesis NIS-SmBiT (Reverse)5’-GCCTCTAGA TTACAGAATCTCCTCGAACAGCCGG TAGCCGGTCACGAGGTTTGTCTCC TGCTG-3’ Sigma-Aldrich Custom synthesis Recombinant DNA pcDNA3.1-EYFP-H148Q/I152L/F46L Alan Verkman’s lab N/A pcDNA3.1-NIS Smith et al., 2009 N/A (Continued on next page) e2 Cell Chemical Biology 29, 502–516.e1–e7, March 17, 2022 .. REAGENT or RESOURCE SOURCE IDENTIFIER Halo-tagSmBiT (negative control) Caroline Gorvin’s lab N/A LgBiT-PRKAR2A (positive control) Caroline Gorvin’s lab N/A SmBiT-PRKACA (positive control) Caroline Gorvin’s lab N/A pcDNA3.1-LgBiT-VCP This paper N/A pcDNA3.1-NIS-SmBiT This paper N/A Software and Algorithms GraphPad Prism Version 9 Graphpad Software Inc https://www.graphpad.com/ scientificsoftware/prism/ ImageJ National Institutes of Health https://imagej.nih.gov/ij/ IBM SPSS Statistics Version 27 IBM https://www.ibm.com/uk-en/products/ spss-statistics BioRender BioRender https://biorender.com/ EC50 Calculator AAT Bioquest https://www.aatbio.com/tools/ec50- calculator GEO2R National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/geo/geo2r/ DynaVenn Chair for Clinical Bioinformatics at Saarland University https://ccb-compute.cs.uni-saarland.de/ dynavenn Other Prestwick Chemical Library Birmingham Drug Discovery Facility https://www.birmingham.ac.uk/facilities/ bddf/compound-collections/index.aspx Opera Phenix High-Content Screening System Perkin Elmer Cat# |